ATG13 Rabbit pAb

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ATG13 Rabbit pAb

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ES20862

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	ATG13 Rabbit pAb
Reactivity:	Human; Mouse;Rat
Alternative Names:	Autophagy-related protein 13
Source:	Rabbit
Dilutions:	IHC-p1:50-200 ,WB 1:1000-2000
Immunogen:	Synthesized peptide derived from human ATG13 AA range: 182-232
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	72kD
GeneID:	9776
Human Swiss-Prot No:	O75143
Cellular localization:	Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Background:	Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

Western blot analysis of 1)Hela Cell, 2) Rat Brain Tissue, 3) Mouse Brainr Tissue Lysate using Rabbit pAb diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).