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ATG4c Rabbit rabbit pAb
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ES20827
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ATG4c Rabbit rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Cysteine protease ATG4C (EC 3.4.22.-;AUT-like 3 cysteine endopeptidase;Autophagin-3;Autophagy-related cysteine endopeptidase 3;Autophagy-related protein 4 homolog C)
Source: Rabbit
Dilutions: IHC-p 1:50-300
Immunogen: Recombinant Protein of ATG4c
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 84938
Human Swiss-Prot No: Q96DT6
Cellular localization: Cytoplasm .
Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008],