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ATG7 Rabbit rabbit pAb
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ES20825
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ATG7 Rabbit rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7;Autophagy-related protein 7;APG7-like;hAGP7;Ubiquitin-activating enzyme E1-like protein)
Source: Rabbit
Dilutions: IHC-p 1:50-300,WB 1:500-2000
Immunogen: Recombinant Protein of ATG7
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 78kD
GeneID: 10533
Human Swiss-Prot No: O95352
Cellular localization: Cytoplasm . Preautophagosomal structure . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. .
Background: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],