Products

Bmi-1 Rabbit rabbit pAb(F270)
One-click to copy product information
ES20814
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Bmi-1 Rabbit rabbit pAb(F270)
Reactivity: Human
Alternative Names: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Recombinant Protein derived from human Bmi-1
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 37-43kD
GeneID: 100532731
Human Swiss-Prot No: P35226
Cellular localization: Nucleus . Cytoplasm .
Background: BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],