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CALHM1 rabbit pAb
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ES20805
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CALHM1 rabbit pAb
Reactivity: Human;Rat
Alternative Names: Calcium homeostasis modulator protein 1; Protein FAM26C
Source: Rabbit
Dilutions: WB: 1:500-1000 IHC: 1:200-500
Immunogen: Synthetic Peptide of CALHM1 AA range: 204-254
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed Band: 40kD
GeneID: 255022
Human Swiss-Prot No: Q8IU99
Cellular localization: Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein . Colocalizes with HSPA5 at the endoplasmic reticulum (PubMed:18585350). Localizes to the basolateral membrane of epithelial cells including taste cells (By similarity). .
Background: calcium homeostasis modulator 1(CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010],