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Cav1.3 rabbit pAb
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ES20797
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cav1.3 rabbit pAb
Reactivity: Human;Rat;Mouse
Alternative Names: Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2;Voltage-gated calcium channel subunit alpha Cav1.3)
Source: Rabbit
Dilutions: IHC 1:100-200
Immunogen: Synthetic Peptide of Cav1.3 AA range: 1060-1140
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 245kD
GeneID: 776
Human Swiss-Prot No: Q01668
Cellular localization: Membrane ; Multi-pass membrane protein .
Background: calcium voltage-gated channel subunit alpha1 D(CACNA1D) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],