| Product name: |
Cav2.2 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Alternative Names: |
Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III;BIII;Calcium channel, L type, alpha-1 polypeptide isoform 5;Voltage-gated calcium channel subunit alpha Cav2.2) |
| Source: |
Rabbit |
| Dilutions: |
IHC 1:50-100 |
| Immunogen: |
Synthetic Peptide of Cav2.2 AA range: 230-310 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
263kD |
| GeneID: |
774 |
| Human Swiss-Prot No: |
Q00975 |
| Cellular localization: |
Membrane ; Multi-pass membrane protein . |
| Background: |
calcium voltage-gated channel subunit alpha1 B(CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011], |
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