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GABA A Receptor α2 rabbit pAb
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ES20750
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GABA A Receptor α2 rabbit pAb
Reactivity: Human;Rat;Mouse
Alternative Names: Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)
Source: Rabbit
Dilutions: WB 1:1000-2000, IHC 1:100-200
Immunogen: Synthetic Peptide of GABA A Receptor α2
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 51kD
GeneID: 282236
Human Swiss-Prot No: P47869
Cellular localization: Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite .
Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],