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Ghrelin Receptor rabbit pAb
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ES20736
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: Ghrelin Receptor rabbit pAb
Reactivity: Human;Rat;Mouse
Alternative Names: Growth hormone secretagogue receptor type 1 (GHS-R;GH-releasing peptide receptor;GHRP;Ghrelin receptor)
Source: Rabbit
Dilutions: WB 1:1000-2000, IHC 1:100-200
Immunogen: Synthetic Peptide of Ghrelin Receptor AA range: 290-370
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 41kD
GeneID: 2693
Human Swiss-Prot No: Q92847
Cellular localization: Cell membrane; Multi-pass membrane protein.
Background: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010],