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KVβ1 rabbit pAb
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ES20681
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50 µL $148.00
100 µL $248.00
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Overview

Product name: KVβ1 rabbit pAb
Reactivity: Human;Rat;Mouse
Alternative Names: Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1;Kv-beta-1)
Source: Rabbit
Dilutions: IHC 1:100-200
Immunogen: Synthetic Peptide of KVβ1 AA range: 66-116
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID: 7881
Human Swiss-Prot No: Q14722
Cellular localization: Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits. .
Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alp