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S100 rabbit pAb
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ES20636
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50 µL $148.00
100 µL $248.00
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Overview

Product name: S100 rabbit pAb
Reactivity: Human;Rat;Mouse
Alternative Names: Protein S100-A1 (S-100 protein alpha chain;S-100 protein subunit alpha;S100 calcium-binding protein A1)
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Recombinant Protein of S100
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 15kD
GeneID: 6271
Human Swiss-Prot No: P23297
Cellular localization: Cytoplasm . Sarcoplasmic reticulum . Mitochondrion .
Background: S100 calcium binding protein A1(S100A1) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008],