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SLUG rabbit pAb
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ES20633
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SLUG rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: SNAI2; SLUG; SLUGH; Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2
Source: Rabbit
Dilutions: WB: 1:500-1000 IHC: 1:200-500
Immunogen: Recombinant Protein of SLUG
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed Band: 30kD
GeneID: 6591
Human Swiss-Prot No: O43623
Cellular localization: Nucleus . Cytoplasm. Observed in discrete foci in interphase nuclei. These nuclear foci do not overlap with the nucleoli, the SP100 and the HP1 heterochromatin or the coiled body, suggesting SNAI2 is associated with active transcription or active splicing regions.
Background: snail family transcriptional repressor 2(SNAI2) Homo sapiens This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008],