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TLR8 rabbit pAb
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ES20603
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TLR8 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Toll-like receptor 8; CD288
Source: Rabbit
Dilutions: IHC: 1:200-500
Immunogen: Recombinant Protein of TLR8
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
GeneID: 51311
Human Swiss-Prot No: Q9NR97
Cellular localization: Endosome membrane ; Single-pass type I membrane protein . Endosomal localization confers distinctive proteolytic processing. .
Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008],