Histone H2A.Z (Acetyl Lys7) rabbit pAb

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Histone H2A.Z (Acetyl Lys7) rabbit pAb

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ES20532

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Histone H2A.Z (Acetyl Lys7) rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	H2AFZ; H2AZ; Histone H2A.Z; H2A/z
Source:	Rabbit
Dilutions:	WB: 1:500-1000
Immunogen:	Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Observed Band:	14kD
GeneID:	3015
Human Swiss-Prot No:	P0C0S5
Cellular localization:	Nucleus. Chromosome.
Background:	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

Western blot analysis of extracts from Hela cells, untreated (-) or treated, 1:5000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).