Products

RFA1 rabbit pAb
One-click to copy product information
ES20438
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: RFA1 rabbit pAb
Reactivity: Human;Monkey;Mouse;Rat
Alternative Names: Replication protein A 70 kDa DNA-binding subunit (RP-A p70;Replication factor A protein 1;RF-A protein 1;Single-stranded DNA-binding protein)
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from human RFA1
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 68kD
GeneID: 6117
Human Swiss-Prot No: P27694
Cellular localization: Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .
Background: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,