Product name: |
COX6c rabbit pAb |
Reactivity: |
Human;Mouse;Rat |
Alternative Names: |
COX6C; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase polypeptide VIc |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human COX6C. AA range:11-60 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
32kD |
GeneID: |
1345 |
Human Swiss-Prot No: |
P09669 |
Cellular localization: |
Mitochondrion inner membrane ; Single-pass membrane protein . |
Background: |
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010], |