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Calpain 2 (Phospho Ser50) rabbit pAb
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ES20175
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Calpain 2 (Phospho Ser50) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Calpain-2 catalytic subunit (EC 3.4.22.53;Calcium-activated neutral proteinase 2;CANP 2;Calpain M-type;Calpain large polypeptide L2;Calpain-2 large subunit;Millimolar-calpain;M-calpain)
Source: Rabbit
Dilutions: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human Calpain 2 (Phospho Ser50)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 69kD
GeneID: 824
Human Swiss-Prot No: P17655
Cellular localization: Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.
Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],