MMP7 (Cleaved-Tyr95) rabbit pAb

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MMP7 (Cleaved-Tyr95) rabbit pAb

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ES20029

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	MMP7 (Cleaved-Tyr95) rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	Matrilysin (EC 3.4.24.23;Matrin;Matrix metalloproteinase-7;MMP-7;Pump-1 protease;Uterine metalloproteinase)
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	Synthesized peptide derived from human MMP7 (Cleaved-Tyr95)
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	19 29kD
GeneID:	4316
Human Swiss-Prot No:	P09237
Cellular localization:	Secreted, extracellular space, extracellular matrix .
Background:	catalytic activity:Cleavage of 14-Ala-\|-Leu-15 and 16-Tyr-\|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).