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ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb
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ES20006
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb
Reactivity: Human;Mouse
Alternative Names: Integrin alpha-5 (CD49 antigen-like family member E;Fibronectin receptor subunit alpha;Integrin alpha-F;VLA-5;CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 94 110kD
GeneID: 3678
Human Swiss-Prot No: P08648
Cellular localization: Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
Background: function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,