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HABP2 (50k heavy chain, Cleaved-Arg313) rabbit pAb
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ES20004
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50 µL $148.00
100 µL $248.00
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Overview

Product name: HABP2 (50k heavy chain, Cleaved-Arg313) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Hyaluronan-binding protein 2 (EC 3.4.21.-;Factor VII-activating protease;Factor seven-activating protease;FSAP;Hepatocyte growth factor activator-like protein;Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form]
Source: Rabbit
Dilutions: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human HABP2 (50k heavy chain, Cleaved-Arg313)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50 77kD
GeneID: 3026
Human Swiss-Prot No: Q14520
Cellular localization: Secreted . Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Background: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],