Products

EMR2 (Cleaved-Leu517) rabbit pAb
One-click to copy product information
ES19989
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: EMR2 (Cleaved-Leu517) rabbit pAb
Reactivity: Human
Alternative Names: EGF-like module-containing mucin-like hormone receptor-like 2 (EGF-like module receptor 2;CD antigen CD312)
Source: Rabbit
Dilutions: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human EMR2 (Cleaved-Leu517)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 30817
Human Swiss-Prot No: Q9UHX3
Cellular localization: Cell membrane ; Multi-pass membrane protein. Cell projection, ruffle membrane ; Multi-pass membrane protein. Localized at the leading edge of migrating cells. .
Background: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],