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DFF45 (Cleaved-Ser118) rabbit pAb
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ES19985
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50 µL $148.00
100 µL $248.00
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Overview

Product name: DFF45 (Cleaved-Ser118) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit;DFF-45;Inhibitor of CAD;ICAD)
Source: Rabbit
Dilutions: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human DFF45 (Cleaved-Ser118)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 24 36kD
GeneID: 1676
Human Swiss-Prot No: O00273
Cellular localization: Cytoplasm.
Background: function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA and DFFB.,