| Product name: |
CLC-KA rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human CLCNKA. AA range:581-630 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
75kD |
| GeneID: |
1187 |
| Human Swiss-Prot No: |
P51800 |
| Cellular localization: |
Membrane; Multi-pass membrane protein. |
| Background: |
This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
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