| Product name: |
ChemR23 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
CMKLR1; CHEMR23; DEZ; Chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
42kD |
| GeneID: |
1240 |
| Human Swiss-Prot No: |
Q99788 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein . Internalizes efficiently in response to RARRES2. . |
| Background: |
developmental stage:Expressed during bone development.,function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands., |
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