Product name: | CD70 rabbit pAb |
Reactivity: | Human;Rat;Mouse; |
Alternative Names: | CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70 |
Source: | Rabbit |
Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human CD70. AA range:68-117 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 30kD |
GeneID: | 970 |
Human Swiss-Prot No: | P32970 |
Cellular localization: | Membrane ; Single-pass type II membrane protein . |
Background: | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008], |