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ACPH rabbit pAb
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ES18492
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ACPH rabbit pAb
Reactivity: Human;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human ACPH AA range: 255-305
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 81kD
GeneID: 327
Human Swiss-Prot No: P13798
Cellular localization: Cytoplasm.
Background: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008],