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AHR rabbit pAb
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ES18432
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AHR rabbit pAb
Reactivity: Human; Mouse;Rat;Fish
Source: Rabbit
Dilutions: WB 1:500-2000; IF/ICC 1:100-500
Immunogen: Synthesized peptide derived from human AHR AA range: 408-458
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 93kD
GeneID: 196
Human Swiss-Prot No: P35869
Cellular localization: Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .
Background: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],