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AL4A1 rabbit pAb
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ES18407
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AL4A1 rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.5.1.12) (Aldehyde dehydrogenase family 4 member A1)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human AL4A1 AA range: 39-89
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 8659
Human Swiss-Prot No: P30038
Cellular localization: Mitochondrion matrix.
Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009],