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AP4A rabbit pAb
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ES18305
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AP4A rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human AP4A AA range: 93-143
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 16kD
GeneID: 318
Human Swiss-Prot No: P50583
Cellular localization: mitochondrial matrix,
Background: This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011],