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APOC1 Rabbit pAb
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ES18289
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50 µL $148.00
100 µL $248.00
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Overview

Product name: APOC1 Rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Apolipoprotein C-I (Apo-CIB;ApoC-IB;Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB';ApoC-IB')]
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen: Synthesized peptide derived from human APOC1 AA range: 1-50
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 341
Human Swiss-Prot No: P02654
Cellular localization: Secreted .
Background: This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016],