Products

APOC2 Polyclona Antibody
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ES18288
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: APOC2 Polyclona Antibody
Reactivity: Human;Rat;Mouse;
Alternative Names: Apolipoprotein C-II (Apo-CII;ApoC-II;Apolipoprotein C2)
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from human APOC2 AA range: 1-50
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 344
Human Swiss-Prot No: P02655
Cellular localization: Secreted .
Background: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011],