Products

ARC1B rabbit pAb
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ES18273
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: ARC1B rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human ARC1B AA range: 27-77
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 41kD
GeneID: 10095
Human Swiss-Prot No: O15143
Cellular localization: Cytoplasm, cytoskeleton . Nucleus .
Background: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011],