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ASPC1 rabbit pAb
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ES18227
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ASPC1 rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human ASPC1 AA range: 327-377
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 61kD
GeneID: 79058
Human Swiss-Prot No: Q9BZE9
Cellular localization: Endomembrane system ; Peripheral membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Peripheral membrane protein. Cytoplasm . Nucleus .
Background: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011],