BCoR rabbit pAb

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BCoR rabbit pAb

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ES1763

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	BCoR rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	BCOR; KIAA1575; BCL-6 corepressor; BCoR
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human BCOR. AA range:1231-1280
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	192kD
GeneID:	54880
Human Swiss-Prot No:	Q6W2J9
Cellular localization:	Nucleus .
Background:	The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010],

Western Blot analysis of various cells using BCoR Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BCOR Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from COLO cells, using BCOR Antibody. The lane on the right is blocked with the synthesized peptide.