| Product name: |
CEAM6 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen;Normal cross-reacting antigen;CD antigen CD66c) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human CEAM6 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
37kD |
| GeneID: |
4680 |
| Human Swiss-Prot No: |
P40199 |
| Cellular localization: |
Cell membrane; Lipid-anchor, GPI-anchor . Apical cell membrane . Cell surface . Localized to the apical glycocalyx surface. . |
| Background: |
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014], |
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