Products

Cyclin T2 rabbit pAb
One-click to copy product information
ES17150
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Cyclin T2 rabbit pAb
Reactivity: Human; Mouse; Rat
Alternative Names: Cyclin-T2 (CycT2)
Source: Rabbit
Dilutions: IHC-p 1:50-200, WB 1:500-2000
Immunogen: Synthesized peptide derived from human Cyclin T2 AA range: 510-590
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 73kD
GeneID: 905
Human Swiss-Prot No: O60583
Cellular localization: Cytoplasm, perinuclear region . Nucleus . Nucleus in differentiating cells. .
Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],