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DMRT2 rabbit pAb
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ES16928
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50 µL $148.00
100 µL $248.00
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Overview

Product name: DMRT2 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human DMRT2 AA range: 315-365
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 10655
Human Swiss-Prot No: Q9Y5R5
Cellular localization: Nucleus .
Background: The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010],