Products

DOLK rabbit pAb
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ES16915
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: DOLK rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human DOLK AA range: 420-470
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 59kD
GeneID: 22845
Human Swiss-Prot No: Q9UPQ8
Cellular localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Background: The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.[provided by RefSeq, Apr 2010],