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EI24 rabbit pAb
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ES16775
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50 µL $148.00
100 µL $248.00
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Overview

Product name: EI24 rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human EI24 AA range: 107-157
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 37kD
GeneID: 9538
Human Swiss-Prot No: O14681
Cellular localization: Nucleus membrane ; Multi-pass membrane protein . Cytoplasm . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Background: This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014],