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ESX1 rabbit pAb
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ES16662
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ESX1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human ESX1 AA range: 327-377
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 45kD
GeneID: 80712
Human Swiss-Prot No: Q8N693
Cellular localization: Cytoplasm . Nucleus . ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm.
Background: This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010],