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EYS rabbit pAb
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ES16647
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50 µL $148.00
100 µL $248.00
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Overview

Product name: EYS rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: IHC-p 1：50-200
Immunogen: Synthesized peptide derived from human EYS AA range: 2780-2830
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 348kD
GeneID: 346007
Human Swiss-Prot No: Q5T1H1
Cellular localization: Cell projection, cilium, photoreceptor outer segment . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix . Localizes to discrete puncta at, or adjacent to, the photoreceptor connecting cilium (PubMed:27737822). Highly expressed in cone photoreceptor outer segments (PubMed:27737822). Weakly expressed in rod photoreceptor outer segments (By similarity). May localize to the cilium axoneme (PubMed:27846257). May also be secreted into the interphotoreceptor extracellular matrix (PubMed:27737822). .
Background: The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],