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Ezh2 (phospho-Thr311) rabbit pAb
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ES16646
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Ezh2 (phospho-Thr311) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Source: Rabbit
Dilutions: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human Ezh2 (Thr311)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 82kD
GeneID: 2146
Human Swiss-Prot No: Q15910
Cellular localization: Nucleus . Localizes to the inactive X chromosome in trophoblast stem cells. .
Background: enhancer of zeste 2 polycomb repressive complex 2 subunit(EZH2) Homo sapiens This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011],