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F105B rabbit pAb
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ES16641
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50 µL $148.00
100 µL $248.00
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Overview

Product name: F105B rabbit pAb
Reactivity: Human; Mouse
Alternative Names: Protein FAM105B
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human F105B AA range: 284-334
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 90268
Human Swiss-Prot No: Q96BN8
Cellular localization: Cytoplasm .
Background: This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016],