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FAN rabbit pAb
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ES16527
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50 µL $148.00
100 µL $248.00
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Overview

Product name: FAN rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human FAN AA range: 147-197
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 101kD
GeneID: 8439
Human Swiss-Prot No: Q92636
Cellular localization: cytoplasm,cytosol,endomembrane system,extrinsic component of membrane,
Background: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],