Products

FBLI1 rabbit pAb
One-click to copy product information
ES16512
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: FBLI1 rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human FBLI1 AA range: 157-207
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 41kD
GeneID: 54751
Human Swiss-Prot No: Q8WUP2
Cellular localization: Cell junction, focal adhesion . Cytoplasm, cytoskeleton, stress fiber . Associated with actin stress fiber at cell-ECM focal adhesion sites (PubMed:12679033, PubMed:18829455). Isoform 1 and isoform 3 are recruited and localized at actin stress fibers and clustered at cell-EMC adhesion sites through interaction with FERMT2 (PubMed:12679033). Isoform 2 is localized at actin stress fibers (PubMed:12496242). .
Background: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],