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FoxO4 (phospho-Ser193) rabbit pAb
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ES16334
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50 µL $148.00
100 µL $248.00
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Overview

Product name: FoxO4 (phospho-Ser193) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Forkhead box protein O4 (Fork head domain transcription factor AFX1)
Source: Rabbit
Dilutions: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human FoxO4 (Ser193)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID: 4303
Human Swiss-Prot No: P98177
Cellular localization: Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
Background: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],