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G6PC2 rabbit pAb
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ES16294
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50 µL $148.00
100 µL $248.00
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Overview

Product name: G6PC2 rabbit pAb
Reactivity: Human; Mouse
Alternative Names: Glucose-6-phosphatase 2 (G-6-Pase 2) (G6Pase 2) (EC 3.1.3.9) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human G6PC2 AA range: 175-225
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 57818
Human Swiss-Prot No: Q9NQR9
Cellular localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Background: This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],