Products

GGT2 rabbit pAb
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ES16189
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: GGT2 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain]
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human GGT2 AA range: 89-139
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
Human Swiss-Prot No: P36268
Cellular localization: Cytoplasm, perinuclear region . Endoplasmic reticulum . Co-localizes with calnexin in the endoplasmic reticulum.
Background: GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008],