AHA-1 rabbit pAb

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AHA-1 rabbit pAb

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ES1612

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	AHA-1 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300;ELISA 1:5000-20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	38kD
GeneID:	10598
Human Swiss-Prot No:	O95433
Cellular localization:	Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.
Background:	function:Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.,induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG).,similarity:Belongs to the AHA1 family.,subcellular location:May transiently interact with the endoplasmic reticulum.,subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1.,tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.,

Western Blot analysis of various cells using AHA-1 Polyclonal Antibody diluted at 1:1000
Western blot analysis of lysates from HT-29, A549, and K562 cells, using AHSA1 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).