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GUC1A rabbit pAb
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ES15854
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GUC1A rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human GUC1A AA range: 63-113
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 22kD
GeneID: 2978
Human Swiss-Prot No: P43080
Cellular localization: Membrane; Lipid-anchor . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Present at higher levels in cone than in rod outer segments (PubMed:9620085). Subcellular location is not affected by light or dark conditions. .
Background: This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],